Pesquisa sobre:
MANNOSE-BINDING PROTEIN-ASSOCIATED SERINE PROTEASES
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DeCS
Descritor
Inglês
:
Mannose-Binding Protein-Associated Serine Proteases
Descritor
Espanhol
:
Serina Proteasas Asociadas a la Proteína de Unión a la Manosa
Descritor
Português
:
Serina Proteases Associadas a Proteína de Ligação a Manose
Categoria:
D08.811.277.656.300.760.501
D08.811.277.656.959.350.501
D12.776.124.486.274.045.387.875
Definição
Inglês
:
Serum
serine proteases
which participate in
COMPLEMENT ACTIVATION
. They are activated when complexed with the
MANNOSE-BINDING LECTIN
, therefore also known as
Mannose-binding protein-Associated Serine Proteases
(MASPs). They cleave
COMPLEMENT C4
and
COMPLEMENT C2
to form C4b2a, the CLASSICAL PATHWAY
C3 CONVERTASE.
Nota de Indexação
Inglês
:
see SCR for organism-specific terms
Ação Farmacológica:
Immunologic Factors
Nota Histórica
Inglês
:
2006 (1994)
Qualificadores Permitidos
Inglês
:
AD
administration & dosage
AE
adverse effects
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
CT
contraindications
DF
deficiency
DU
diagnostic use
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
SE
secretion
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Número do Registro:
50582
Identificador Único:
D050606
Ocorrência na BVS
:
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CID-10
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